This medication regimen typically involves two pills: mifepristone and misoprostol. You’ll take mifepristone first, usually at a clinic. This pill blocks the hormone progesterone, necessary for pregnancy continuation. Twenty-four to 48 hours later, you’ll take misoprostol, which causes cramping and bleeding, expelling the pregnancy.
Mifepristone: The First Step
Expect some mild cramping or spotting after taking mifepristone. Rest is recommended. Follow your provider’s specific instructions regarding medication timing.
Misoprostol: Completing the Process
Misoprostol is taken orally or vaginally, as directed by your healthcare provider. Expect heavier bleeding and stronger cramping than with mifepristone. This is a normal part of the process. Pain medication, like ibuprofen, may help manage discomfort.
Important Considerations
| Bleeding | Expect bleeding similar to a heavy menstrual period, lasting several days to weeks. |
| Cramping | Cramps can range from mild to severe. Over-the-counter pain relievers can help. |
| Follow-up | A follow-up appointment with your provider is crucial to confirm the pregnancy has ended. This appointment will allow for proper monitoring and provide you with further guidance. Expect an ultrasound to confirm pregnancy termination. |
| Side Effects | Nausea, vomiting, diarrhea, and fatigue are possible. Contact your healthcare provider if you experience severe symptoms. |
Remember, this information is for general understanding and should not replace advice from your healthcare provider. Always consult a medical professional before making decisions about your health.


