Drug Interactions with Azithromycin

Always inform your doctor about all medications you’re taking, including over-the-counter drugs, herbal supplements, and vitamins, before starting azithromycin. This helps prevent potential interactions.

Certain medications can significantly affect how azithromycin works, or vice versa. For instance, azithromycin can increase the levels of some drugs in your blood, potentially causing side effects. Conversely, other drugs can reduce azithromycin’s effectiveness.

Medication Class Specific Examples Potential Interaction
Anticoagulants (blood thinners) Warfarin, Coumadin Increased bleeding risk; monitor INR closely.
Ergot alkaloids Ergotamine, dihydroergotamine Increased risk of ergotism (peripheral vasoconstriction); avoid concurrent use.
Statins (cholesterol-lowering drugs) Simvastatin, atorvastatin Increased risk of myopathy (muscle damage); monitor for muscle pain or weakness.
Digoxin (heart medication) Digoxin Increased digoxin levels; monitor digoxin levels.
Pimozide (antipsychotic) Pimozide Increased risk of QT prolongation (heart rhythm abnormality); avoid concurrent use.
Cisapride (gastrointestinal motility drug) Cisapride Increased risk of QT prolongation; avoid concurrent use.
Antacids Many brands May reduce azithromycin absorption; separate administration by at least 2 hours.

This table is not exhaustive. Many other drugs may interact with azithromycin. Always consult your physician or pharmacist for personalized advice before combining azithromycin with other medications.

Failing to disclose all medications can lead to unforeseen health complications. Open communication with your healthcare provider is paramount for safe and effective treatment.