Lisinopril, while effective, can cause side effects. Dry cough is common; it often resolves on its own, but talk to your doctor if it’s persistent or bothersome. They might suggest an alternative ACE inhibitor or a different medication entirely.
Dizziness and lightheadedness are also possible. Get up slowly from a lying or sitting position to minimize this risk. Staying well-hydrated can help.
High potassium levels (hyperkalemia) are a concern, especially for those with kidney problems or diabetes. Your doctor will monitor your potassium levels regularly. Avoid potassium supplements and potassium-rich foods like bananas and oranges if advised.
Lisinopril interacts with several medications. Always inform your doctor and pharmacist of all medications, including over-the-counter drugs and supplements, you’re taking. This is particularly important with potassium-sparing diuretics, NSAIDs (like ibuprofen and naproxen), and potassium supplements, as these combinations can increase your risk of hyperkalemia.
| Potassium-sparing diuretics (e. g., spironolactone) | Increased risk of hyperkalemia | Usually avoided in combination |
| NSAIDs (e. g., ibuprofen, naproxen) | Reduced effectiveness of lisinopril | Monitor blood pressure closely |
| Lithium | Increased lithium levels | Monitor lithium levels regularly |
If you experience any unusual symptoms while taking lisinopril, contact your doctor immediately. Don’t stop taking lisinopril abruptly without consulting your doctor; this could be harmful.


